Scientist/Senior Scientist (Cell Science)
Location: Babraham Research Campus, Cambridge
Salary Range: £29,000-£37,000 (Scientist); £35,000-£47,000 (Senior Scientist) flexible according to experience
Contract: Full Time 35 hours per week, Permanent
Application method: Please provide a CV, you will also be asked a few short application questions relating to your experience and suitability for this position
Closing date: We will be reviewing applications as they are submitted and this vacancy will close once a suitable candidate is found. Please do not delay to submit an application at your earliest convenience in order to avoid any disappointment
Cancer Research UK's Therapeutic Discovery Laboratories (CRUK-TDL), is the in-house CRUK drug discovery unit with a principal focus on establishing and prosecuting biologically themed, multi-project alliances with industrial partners. Based at the Babraham Research Campus in Cambridge, and the Crick Institute in London, TDL comprises over 90 staff from both industrial and academic backgrounds.
We bring together the best minds in basic and clinical cancer research, the diligence and drive of pharmaceutical and biotech companies, and our in-house drug discovery and Alliance management capabilities to deliver breakthrough medicines for cancer patients.
Why we need you
Our laboratories house the personnel and equipment to progress projects from initial hypothesis through to selection of candidate drugs for regulatory development. We couple this with a deep understanding of academic and industrial drivers, enabling us to build alliances that satisfy the curiosity of basic research and the rigour of drug discovery.
We are currently recruiting for a laboratory-based position, at either Senior Scientist or Scientist level (dependent upon experience), to join CRUK-TDL’s Discovery Bioscience Screening and Compound Profiling team. We develop biochemical, biophysical and cell-based assays, run mechanism of action studies, carry out high throughput screening campaigns and run regular structure activity relationship-profiling assays. This role will primarily be focussed on the development and running of cellular assays to identify, profile and characterise the SAR biology of small molecules and antibodies, and also in the bespoke characterisation of their mechanism of action to inform dose prediction and clinical efficacy. However, development opportunities are also likely to arise for a strong candidate to work across other areas of the department.
As a Scientist or Senior Scientist, you will form an integral part of the CRUK-TDL team working alongside our industry and academic partners to progress novel cancer targets towards patient benefit.
What skills are we looking for?
To join us as a Senior Scientist you will have…
- A PhD level qualification with post-doctoral experience, or equivalent biopharma experience in biochemistry, pharmacology or a related discipline
- Significant research experience in a drug discovery environment of characterising targets and their modulation by small molecules through quantitative cell biology
- Demonstrated theoretical and practical understanding of Pharmacology and drug-target interactions
- Demonstrated scientific leadership skills
- Proficiency in assay development in a range of quantitative cell assay technologies (including proliferation, ELISA, reporter, immunofluorescence, 2/3D colony formation, flow cytometry, incucyte, MSD, HTRF, alphaLISA, co-culture assays and cytokine profiling)
- Experience of liquid handling and automation would be an advantage
To join us as a Scientist you will have…
- A PhD level qualification, or equivalent biopharma experience in biochemistry, pharmacology or a related discipline
- Research experience in a drug discovery environment and compound handling would be highly desirable
- Proficiency in a range of quantitative cell assay technologies (including proliferation, ELISA, reporter, immunofluorescence, 2/3D colony formation, flow cytometry, incucyte, MSD, HTRF, alphaLISA, co-culture assays and cytokine profiling)
- Experience of liquid handling and automation would be an advantage
To see a full job description for both roles please click here: https://adobe.ly/3qDloND
What will I gain?
Without you we wouldn’t be able to achieve our aim of seeing 3 in 4 people survive cancer by 2034. So, we want to reward you in as many ways as possible. Our benefits package includes discounts on anything from travel to technology, generous holiday allowance, gym membership, childcare vouchers and much more. You’ll also be able to access a wide range of learning and development opportunities. And ultimately, you’ll know that you’ll be changing lives through your work.
If you’re as ambitious as we are, join our collective force and enjoy an excellent career, as we save lives and add years.